2008 ICD-9-CM Volume 1 Diagnosis Codes Home > Endocrine, Nutritional And Metabolic Diseases, And Immunity Disorders 240-279 > Other Metabolic Disorders And Immunity Disorders 270-279 > Disorders Of Plasma Protein Metabolism 273.* >  2008 ICD-9-CM Diagnosis 273.3
Macroglobulinemia On October 1, 2008 the 2009 ICD-9-CM codes came into effect. Therefore, this code may be out of date.
The 2009 version of ICD-9-CM 273.3 can be accessed here. - (MAK-ro-GLOB-u-li-NE-me-uh) A condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is Waldenstrom's macroglobulinemia, which is a type of cancer.
- A clonal neoplasm of small B-lymphocytes, lymphoplasmacytoid cells, and plasma cells involving the bone marrow, lymph nodes, and the spleen. The majority of patients have a serum IgM paraprotein. Lymphoplasmacytic lymphoma/ Waldenstrom's Macroglobulinemia is a relatively rare condition accounting for approximately 2% of hematologic malignancies. Symptoms include: weakness and fatigue, hemorrhagic manifestations, weight loss and visual disturbances. Physical findings include: hepatomegaly, splenomegaly, fundic changes, adenopathy, neurologic abnormalities and purpura. The most common laboratory finding is anemia. Treatment includes: chemotherapy (alkylating agents, nucleoside analogues) radiotherapy and plasmapheresis. Bone marrow transplant is being investigated. Asymptomatic patients may be monitored without treatment until complications occur. - 2003
- A plasma cell dyscrasia resembling leukemia with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an IMMUNOGLOBULIN M monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed)
- A rare cancer of the lymph cells that causes the body to produce abnormal levels of plasma cells (plasmacytosis) and lymphocytes (lymphocytosis) in the bone marrow. Waldenstrom's macroglobulinemia may also cause a decrease in the number of red blood cells (anemia) and enlargement of the liver (hepatomegaly), spleen (splenomegaly), or glands (adenopathy).
- see also M-9671/3
- 273.3 is a specific code that can be used to specify a diagnosis
- 273.3 contains 9 index entries
- View the ICD-9-CM Volume 1 273.* hierarchy
ICD9Data's sister site ProcedureCodes.com launches with the 2008/09 CPT® codes - read more on the ICD9Data.com blog. 273.3 also known as:- Macroglobulinemia (idiopathic) (primary)
- Waldenström's macroglobulinemia
Index entries containing 273.3:- Gammopathy 273.9
- macroglobulinemia
 273.3
Hyperviscosity (of serum) (syndrome) NEC 273.3Macroglobulinemia (essential) (idiopathic) (monoclonal) (primary) (syndrome) (Waldenström's) 273.3
Syndrome - see also Disease- African macroglobulinemia 273.3
- hyperviscosity (of serum) NEC 273.3
- macroglobulinemia 273.3
- Waldenström's (macroglobulinemia) 273.3
Waldenström's- macroglobulinemia 273.3
- syndrome (macroglobulinemia) 273.3
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