2013 ICD-9-CM Diagnosis Code 273.3
Macroglobulinemia
- plasma cell dyscrasia resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, that secrete an IgM monoclonal component.
- A rare cancer of the lymph cells that causes the body to produce abnormal levels of plasma cells (plasmacytosis) and lymphocytes (lymphocytosis) in the bone marrow. Waldenstrom's macroglobulinemia may also cause a decrease in the number of red blood cells (anemia) and enlargement of the liver (hepatomegaly), spleen (splenomegaly), or glands (adenopathy).
- (MAK-ro-GLOB-u-li-NE-me-uh) A condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is Waldenstrom's macroglobulinemia, which is a type of cancer.
- A clonal neoplasm of small B-lymphocytes, lymphoplasmacytoid cells, and plasma cells involving the bone marrow, lymph nodes, and the spleen. The majority of patients have a serum IgM paraprotein. Lymphoplasmacytic lymphoma/Waldenstrom's Macroglobulinemia is a relatively rare condition accounting for approximately 2% of hematologic malignancies. Symptoms include: weakness and fatigue, hemorrhagic manifestations, weight loss, and visual disturbances. Physical findings include: hepatomegaly, splenomegaly, fundic changes, adenopathy, neurologic abnormalities, and purpura. The most common laboratory finding is anemia. Treatment includes: chemotherapy (alkylating agents, nucleoside analogues) radiotherapy, and plasmapheresis. Bone marrow transplant is being investigated. Asymptomatic patients may be monitored without treatment until complications occur.
- ICD-9-CM 273.3 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Applies To
Convert 273.3 to ICD-10-CM 
ICD-9-CM Volume 2 Index entries containing back-references to 273.3:
macroglobulinemia 
polycythemic 
