Specific code 2014 ICD-9-CM Diagnosis Code 273.3
Macroglobulinemia
  • Billable Code
  • ICD-9-CM 273.3 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 273.3 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Disease Synonyms
  • Waldenstrom macroglobulinemia
  • Waldenström macroglobulinemia
  • Waldenstroms macroglobulinemia
Clinical Information
  • (mak-ro-glob-u-li-ne-me-uh) a condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is waldenstrom's macroglobulinemia, which is a type of cancer.
  • A clonal neoplasm of small b-lymphocytes, lymphoplasmacytoid cells, and plasma cells involving the bone marrow, lymph nodes, and the spleen. The majority of patients have a serum igm paraprotein. Lymphoplasmacytic lymphoma/waldenstrom's macroglobulinemia is a relatively rare condition accounting for approximately 2% of hematologic malignancies. Symptoms include: weakness and fatigue, hemorrhagic manifestations, weight loss, and visual disturbances. Physical findings include: hepatomegaly, splenomegaly, fundic changes, adenopathy, neurologic abnormalities, and purpura. The most common laboratory finding is anemia. Treatment includes: chemotherapy (alkylating agents, nucleoside analogues) radiotherapy, and plasmapheresis. Bone marrow transplant is being investigated. Asymptomatic patients may be monitored without treatment until complications occur.
  • A lymphoproliferative disorder characterized by pleomorphic b-lymphocytes including plasma cells, with increased levels of monoclonal serum immunoglobulin m. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include anemia; hemorrhages; and hyperviscosity.
  • A rare cancer of the lymph cells that causes the body to produce abnormal levels of plasma cells (plasmacytosis) and lymphocytes (lymphocytosis) in the bone marrow. Waldenstrom's macroglobulinemia may also cause a decrease in the number of red blood cells (anemia) and enlargement of the liver (hepatomegaly), spleen (splenomegaly), or glands (adenopathy).
  • An indolent (slow-growing) type of non-hodgkin lymphoma marked by abnormal levels of igm antibodies in the blood and an enlarged liver, spleen, or lymph nodes.
  • Lymphoplasmacytic lymphoma associated with bone marrow involvement and igm monoclonal gammopathy.
  • Plasma cell dyscrasia resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, that secrete an igm monoclonal component.
Applies To
  • Macroglobulinemia (idiopathic) (primary)
  • Waldenström's macroglobulinemia
Convert to ICD-10-CM: 273.3 converts approximately to:
  • 2014 ICD-10-CM C88.0 Waldenström macroglobulinemia
ICD-9-CM Volume 2 Index entries containing back-references to 273.3:
  • Gammopathy 273.9
    • macroglobulinemia 273.3
  • Hyperviscosity (of serum) (syndrome) NEC 273.3
  • Macroglobulinemia (essential) (idiopathic) (monoclonal) (primary) (syndrome) (Waldenström's) 273.3
  • Syndrome - see also Disease
    • African macroglobulinemia 273.3
    • hyperviscosity (of serum) NEC 273.3
    • macroglobulinemia 273.3
    • Waldenström's (macroglobulinemia) 273.3
  • Waldenström's
    • macroglobulinemia 273.3
    • syndrome (macroglobulinemia) 273.3
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 273.3 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.