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2008 ICD-9-CM Volume 1 Diagnosis Codes Home > Endocrine, Nutritional And Metabolic Diseases, And Immunity Disorders 240-279 > Other Metabolic Disorders And Immunity Disorders 270-279 >

ICD-9-CM Diagnosis 273

Disorders of plasma protein metabolism

  • 273 is a non-specific code that cannot be used to specify a diagnosis


ICD-9-CM Diagnosis 273.0

Polyclonal hypergammaglobulinemia

  • 273.0 is a specific code that can be used to specify a diagnosis
  • 273.0 contains 5 index entries

ICD-9-CM Diagnosis 273.1

Monoclonal paraproteinemia

  • Conditions characterized by the presence of a monoclonal serum (or urine) protein without clinical manifestations of plasma cell dyscrasia.
  • 273.1 is a specific code that can be used to specify a diagnosis
  • 273.1 contains 9 index entries

ICD-9-CM Diagnosis 273.2

Other paraproteinemias

  • A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Paraproteinemias may be seen in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases. --2004
  • 273.2 is a specific code that can be used to specify a diagnosis
  • 273.2 contains 10 index entries

ICD-9-CM Diagnosis 273.3

Macroglobulinemia

  • (MAK-ro-GLOB-u-li-NE-me-uh) A condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is Waldenstrom's macroglobulinemia, which is a type of cancer.
  • A clonal neoplasm of small B-lymphocytes, lymphoplasmacytoid cells, and plasma cells involving the bone marrow, lymph nodes, and the spleen. The majority of patients have a serum IgM paraprotein. Lymphoplasmacytic lymphoma/ Waldenstrom's Macroglobulinemia is a relatively rare condition accounting for approximately 2% of hematologic malignancies. Symptoms include: weakness and fatigue, hemorrhagic manifestations, weight loss and visual disturbances. Physical findings include: hepatomegaly, splenomegaly, fundic changes, adenopathy, neurologic abnormalities and purpura. The most common laboratory finding is anemia. Treatment includes: chemotherapy (alkylating agents, nucleoside analogues) radiotherapy and plasmapheresis. Bone marrow transplant is being investigated. Asymptomatic patients may be monitored without treatment until complications occur. - 2003
  • A plasma cell dyscrasia resembling leukemia with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an IMMUNOGLOBULIN M monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed)
  • A rare cancer of the lymph cells that causes the body to produce abnormal levels of plasma cells (plasmacytosis) and lymphocytes (lymphocytosis) in the bone marrow. Waldenstrom's macroglobulinemia may also cause a decrease in the number of red blood cells (anemia) and enlargement of the liver (hepatomegaly), spleen (splenomegaly), or glands (adenopathy).
  • see also M-9671/3
  • 273.3 is a specific code that can be used to specify a diagnosis
  • 273.3 contains 9 index entries


ICD-9-CM Diagnosis 273.4

Alpha-1-antitrypsin deficiency

  • Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN, leading primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. (From Scriver, Beaudet, Sly, & Valle, The Metabolic and Molecular Bases of Inherited Disease, 7th ed, p4125)
  • 273.4 is a specific code that can be used to specify a diagnosis
  • 273.4 contains 6 index entries

ICD-9-CM Diagnosis 273.8

Other disorders of plasma protein metabolism

  • 273.8 is a specific code that can be used to specify a diagnosis
  • 273.8 contains 17 index entries

ICD-9-CM Diagnosis 273.9

Unspecified disorder of plasma protein metabolism

  • 273.9 is a specific code that can be used to specify a diagnosis
  • 273.9 contains 3 index entries