Specific code 2014 ICD-9-CM Diagnosis Code 446.21
Goodpasture's syndrome
  • Billable Code
  • ICD-9-CM 446.21 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 446.21 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Clinical Information
  • An autoimmune disease of the kidney and the lung. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of collagen type iv in the basement membranes of kidney glomeruli (kidney glomerulus) and lung alveoli (pulmonary alveoli), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
  • An autoimmune disorder characterized by pulmonary hemorrhage and glomerulonephritis. It is a hypersensitivity reaction resulting in the formation of antibodies against the pulmonary alveoli and the basement membrane of the glomeruli.
  • An autoimmune disorder characterized by the production of autoantibodies against type iv collagen of the glomerular basement membrane of the kidney. In the majority of patients the immune reaction also extends to the alveolar capillary membrane of the lungs. The latter cases are referred to as goodpasture syndrome.
  • Combination of pulmonary hemorrhage and glomerulonephritis; known also as the lung purpura glomerulonephritis complex; considered by some to be a form of hypersensitivity reaction.
Applies To
  • Antiglomerular basement membrane antibody-mediated nephritis with pulmonary hemorrhage
Use Additional
  • Use additional code to identify renal disease (583.81)
Convert to ICD-10-CM: 446.21 converts approximately to:
  • 2014 ICD-10-CM M31.0 Hypersensitivity angiitis
ICD-9-CM Volume 2 Index entries containing back-references to 446.21:
  • Angiitis 447.6
    • hypersensitivity 446.20
      • Goodpasture's syndrome 446.21
      • specified NEC 446.29
  • Goodpasture's syndrome (pneumorenal) 446.21
  • Hemorrhage, hemorrhagic (nontraumatic) 459.0
    • pulmonary (see also Hemorrhage, lung) 786.30
      • acute idiopathic in infants (AIPHI) (over 28 days old) 786.31
      • newborn (massive) 770.3
      • renal syndrome 446.21
    • renal 593.81
      • pulmonary syndrome 446.21
  • Syndrome - see also Disease
    • Goodpasture's (pneumorenal) 446.21
    • pulmonary
      • arteriosclerosis 416.0
      • hypoperfusion (idiopathic) 769
      • renal (hemorrhagic) 446.21
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 446.21 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.