2015 ICD-9-CM Diagnosis Code 258.0
Polyglandular activity in multiple endocrine adenomatosis
- There are 3 ICD-9-CM codes below 258.0 that define this diagnosis in greater detail. Do not use this code on a reimbursement claim.
- An autosomal dominant inherited neoplastic syndrome characterized by the development of various endocrine neoplasms and abnormalities in various anatomic sites. There are three types recognized: type 1 (men 1), caused by inactivation of the tumor suppressor gene men-1, type 2a (men 2a), caused by mutation of the ret gene, and type 2b (men 2b) also caused by mutation of the ret gene. Patients with men 1 may develop hyperparathyroidism and parathyroid gland adenomas, pituitary gland adenomas, pancreatic islet cell neoplasms, and carcinoid tumors. Patients with men 2a develop medullary thyroid carcinomas, and may also develop pheochromocytomas and parathyroid gland hyperplasia. Patients with men 2b develop medullary thyroid carcinomas and numerous neural defects including neuromas
- An inherited tendency to develop thyroid cancer and other cancers of the endocrine system. The altered gene can be detected with a blood test
- Group of specific, familial syndromes characterized by simultaneous neoplastic transformation of multiple endocrine tissues, typically the parathyroid glands, pancreatic islets, and anterior pituitary
- Multiple endocrine neoplasia [MEN] syndromes
- Use additional codes to identify any malignancies and other conditions associated with the syndromes