Specific code 2014 ICD-9-CM Diagnosis Code 759.5
Tuberous sclerosis
  • Billable Code
  • ICD-9-CM 759.5 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 759.5 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Disease Synonyms
  • Tuberous sclerosis syndrome
Clinical Information
  • A genetic disorder in which benign (not cancer) tumors form in the kidneys, brain, eyes, heart, lungs, and skin. This disease can cause seizures, mental disabilities, and different types of skin lesions.
  • A triad of epilepsy, mental retardation, and angiofibromas of numerous organs with intracranial hamartomatous lesions involving subependymal nodules and cerebral cortical tubers (hence the name "tuberous sclerosis."
  • Autosomal dominant disease characterized principally by the presences of hamartomas of the brain, retina, and visera; clinical manifestations include mental retardation, seizures, and adenoma sebaceum of the face.
  • Autosomal dominant neurocutaneous syndrome classically characterized by mental retardation; epilepsy; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and hamartomas formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci tsc1 and tsc2 that encode hamartin and tuberin, respectively, are associated with the disease.
  • Hereditary disease characterized by seizures, mental retardation, developmental delay, and skin and ocular lesions. First signs usually occur during infancy or childhood but in rare cases may not occur until 2nd or 3rd decade.
  • Tuberous sclerosis is a rare genetic disease that causes noncancerous tumors to grow in the brain and other organs. Symptoms vary depending on the location of the tumors. Common symptoms include
    • skin problems, such as light patches and thickened skin
    • seizures
    • behavior problems
    • learning disabilities
    • mental retardation
    • kidney problems
    some people have signs of tuberous sclerosis at birth. In others it can take time for the symptoms to develop. In some people the disease is mild, while in others it causes severe disabilities. In rare cases, tumors in vital organs or other symptoms can be life-threatening. Tuberous sclerosis has no cure, but treatments can help symptoms. Options include medicines, educational and occupational therapy, dermabrasion, and surgery.
Applies To
  • Bourneville's disease
  • Epiloia
Convert to ICD-10-CM: 759.5 converts directly to:
  • 2014 ICD-10-CM Q85.1 Tuberous sclerosis
ICD-9-CM Volume 2 Index entries containing back-references to 759.5:
  • Adenoma (sessile) (M8140/0) - see also Neoplasm, by site, benign
    • sebaceous, sebaceum (gland) (senile) (M8410/0) - see also Neoplasm, skin, benign
      • disseminata 759.5
  • Bourneville's disease (tuberous sclerosis) 759.5
  • Disease, diseased - see also Syndrome
    • Bourneville (-Brissaud) (tuberous sclerosis) 759.5
    • Pringle's (tuberous sclerosis) 759.5
  • Epiloia 759.5
  • Neurinomatosis (M9560/1) - see also Neoplasm, connective tissue, uncertain behavior
    • centralis 759.5
  • Neurospongioblastosis diffusa 759.5
  • Nevus (M8720/0) - see also Neoplasm, skin, benign
    • multiplex 759.5
  • Pringle's disease (tuberous sclerosis) 759.5
  • Sclerosis, sclerotic
    • tuberous (brain) 759.5
  • Syndrome - see also Disease
    • Bourneville (-Pringle) (tuberous sclerosis) 759.5
  • Tuberous sclerosis (brain) 759.5
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 759.5 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.