Non-specific code 2014 ICD-9-CM Diagnosis Code 279.5
Graft-versus-host disease
  • Non-Billable Code
  • There are 4 ICD-9-CM codes below 279.5 that define this diagnosis in greater detail. Do not use this code on a reimbursement claim.
Clinical Information
  • A disease caused when cells from a donated stem cell graft attack the normal tissue of the transplant patient. Symptoms include jaundice, skin rash or blisters, a dry mouth, or dry eyes.
  • A reaction of donated bone marrow or peripheral stem cells against a person's tissue.
  • An incompatibility reaction (which may be fatal) in a subject (host) of low immunological competence (deficient lymphoid tissue) who has been the recipient of immunologically competent lymphoid tissue from a donor who lacks at least one antigen possessed by the recipient host; the reaction, or disease, is the result of action of the transplanted cells against those host tissues that possess the antigen not possessed by the donor. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin.
  • Caused by immunologically competent t cells in the graft recognizing and attacking host tissues as foreign; clinical symptoms include skin rashes, diarrhea, and abnormal liver functions.
  • The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft vs host reaction.
Code First
  • Code first underlying cause, such as:
    • complication of blood transfusion (999.89)
    • complication of transplanted organ (996.80-996.89)
Use Additional
  • Use additional code to identify associated manifestations, such as:
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 279.5 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.