Specific code 2014 ICD-9-CM Diagnosis Code 255.0
Cushing's syndrome
  • Billable Code
  • ICD-9-CM 255.0 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 255.0 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Disease Synonyms
  • Adrenal Cushing's syndrome
  • Adrenocorticotropic hormone -dependent Cushing's syndrome
  • Alcohol-induced pseudo-Cushing's syndrome
  • Artefactual pseudo-Cushing's syndrome
  • Cushing disease
  • Cushing syndrome
  • Cushing syndrome myopathy
  • Cushing's syndrome, myopathy
  • Cushings, iatrogenic
  • Cyclical Cushing's syndrome
  • Hypercortisolism
  • Hypercortisolism due to adrenal neoplasm
  • Hypercortisolism due to nonpituitary tumor
  • Hypercortisolism due to pituitary adenoma
  • Hypermelanosis due to Cushing syndrome
  • Iatrogenic Cushing syndrome
  • Iatrogenic Cushing's disease
  • Idiopathic Cushing's syndrome
  • Myopathy due to Cushing's syndrome
  • Myopathy in Cushing's disease
  • Nelson syndrome
  • Paraneoplastic ectopic secretion of ACTH
  • Pituitary dependent hypercortisolism
  • Pituitary-dependent Cushing's disease
  • Pseudo-Cushing syndrome due to alcohol
  • Steroid induced cushing syndrome
Clinical Information
  • A syndrome characterized by abnormal secretion of adrenocorticotrophic hormone in conjunction with neoplastic growth occurring anywhere in the body. The most common associations are tumors of the bronchus (oat cell or carcinoid), thymic tumors (epithelial or carcinoid), and pancreatic endocrine tumor. (devita et al. Cancer, p 1364. 4th edition. Lippincott)
  • Abnormally increased secretion of adrenal hormones.
  • Complex of symptoms and signs due to excessive production or administration of hydrocortisone or its semi-synthetic analogs.
  • Condition, more commonly seen in females, due to hyperadrenocorticism resulting from neoplasms of the adrenal cortex or the anterior lobe of the pituitary, or to prolonged excessive intake of glucocorticoids for therapeutic purposes; symptoms and signs may include rapidly developing adiposity of the face, neck, and trunk, kyphosis caused by osteoporosis of the spine, hypertension, diabetes mellitus, amenorrhea, hypertrichosis in females, impotence in males, dusky complexion with purple markings, polycythemia, pain in the abdomen and back, and muscular wasting and weakness.
255.0 Excludes
  • congenital adrenal hyperplasia (255.2)
Applies To
  • Adrenal hyperplasia due to excess ACTH
  • Cushing's syndrome:
    • NOS
    • iatrogenic
    • idiopathic
    • pituitary-dependent
  • Ectopic ACTH syndrome
  • Iatrogenic syndrome of excess cortisol
  • Overproduction of cortisol
Use Additional
  • Use additional E code to identify cause, if drug-induced
Convert to ICD-10-CM: 255.0 converts approximately to:
  • 2014 ICD-10-CM E24.0 Pituitary-dependent Cushing's disease
    Or:
  • 2014 ICD-10-CM E24.2 Drug-induced Cushing's syndrome
    Or:
  • 2014 ICD-10-CM E24.3 Ectopic ACTH syndrome
    Or:
  • 2014 ICD-10-CM E24.8 Other Cushing's syndrome
    Or:
  • 2014 ICD-10-CM E24.9 Cushing's syndrome, unspecified
ICD-9-CM Volume 2 Index entries containing back-references to 255.0:
  • Basophilism (corticoadrenal) (Cushing's) (pituitary) (thymic) 255.0
  • Cushing's
    • basophilism, disease, or syndrome (iatrogenic) (idiopathic) (pituitary basophilism) (pituitary dependent) 255.0
  • Cushingoid due to steroid therapy
    • correct substance properly administered 255.0
  • Disease, diseased - see also Syndrome
    • Cushing's (pituitary basophilism) 255.0
  • Ectopic, ectopia (congenital) 759.89
    • ACTH syndrome 255.0
    • secretion
      • ACTH 255.0
      • adrenal hormone 259.3
      • adrenalin 259.3
      • adrenocorticotropin 255.0
      • antidiuretic hormone (ADH) 259.3
      • epinephrine 259.3
      • hormone NEC 259.3
      • norepinephrine 259.3
      • pituitary (posterior) 259.3
  • Hyperplasia, hyperplastic
    • adrenal (capsule) (cortex) (gland) 255.8
      • with
        • sexual precocity (male) 255.2
        • virilism, adrenal 255.2
        • virilization (female) 255.2
      • congenital 255.2
      • due to excess ACTH (ectopic) (pituitary) 255.0
      • medulla 255.8
  • Hypersecretion
    • cortisol 255.0
  • Iatrogenic syndrome of excess cortisol 255.0
  • Inappropriate
    • secretion
      • ACTH 255.0
      • antidiuretic hormone (ADH) (excessive) 253.6
      • ectopic hormone NEC 259.3
      • pituitary (posterior) 253.6
  • Itsenko-Cushing syndrome (pituitary basophilism) 255.0
  • Overproduction - see also Hypersecretion
    • cortisol 255.0
  • Steroid
    • effects (adverse) (iatrogenic)
      • cushingoid
        • correct substance properly administered 255.0
        • overdose or wrong substance given or taken 962.0
      • diabetes - see Diabetes, secondary
        • correct substance properly administered 251.8
        • overdose or wrong substance given or taken 962.0
      • due to
        • correct substance properly administered 255.8
        • overdose or wrong substance given or taken 962.0
      • fever
        • correct substance properly administered 780.60
        • overdose or wrong substance given or taken 962.0
      • withdrawal
        • correct substance properly administered 255.41
        • overdose or wrong substance given or taken 962.0
  • Syndrome - see also Disease
    • Cushing's (iatrogenic) (idiopathic) (pituitary basophilism) (pituitary-dependent) 255.0
      • overdose or wrong substance given or taken 962.0
    • ectopic ACTH secretion 255.0
    • excess cortisol, iatrogenic 255.0
    • Itsenko-Cushing (pituitary basophilism) 255.0
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 255.0 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.