Specific code 2014 ICD-9-CM Diagnosis Code 251.5
Abnormality of secretion of gastrin
  • Billable Code
  • Short description: Abnorm secretion gastrin.
  • ICD-9-CM 251.5 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 251.5 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Disease Synonyms
  • Hypergastrinemia
  • Increased gastrin secretion
Clinical Information
  • A disorder in which tumors of the pancreatic islet cells produce large amounts of gastrin (a hormone), leading to excess acid in the stomach and, possibly, a peptic ulcer (ulcer of the stomach or the upper part of the small intestine).
  • Triad comprising intractable, sometimes fulminating atypical ulcers, extremely elevated gastic acidity, and gastrin secreting non beta islet cell tumors.
Applies To
  • Hyperplasia of pancreatic alpha cells with gastrin excess
  • Zollinger-Ellison syndrome
Convert to ICD-10-CM: 251.5 converts directly to:
  • 2014 ICD-10-CM E16.4 Increased secretion of gastrin
ICD-9-CM Volume 2 Index entries containing back-references to 251.5:
  • Abnormal, abnormality, abnormalities - see also Anomaly
    • gastrin secretion 251.5
    • secretion
      • gastrin 251.5
      • glucagon 251.4
  • Ellison-Zollinger syndrome
    • (gastric hypersecretion with pancreatic islet cell tumor) 251.5
  • Excess, excessive, excessively
    • gastrin 251.5
  • Hyperplasia, hyperplastic
    • alpha cells (pancreatic)
      • with
        • gastrin excess 251.5
        • glucagon excess 251.4
    • islet cell (pancreatic) 251.9
      • alpha cells
        • with excess
          • gastrin 251.5
          • glucagon 251.4
      • beta cells 251.1
    • pancreatic islet cells 251.9
      • alpha
        • with excess
          • gastrin 251.5
          • glucagon 251.4
      • beta 251.1
  • Hypersecretion
    • gastrin 251.5
  • Syndrome - see also Disease
    • Ellison-Zollinger (gastric hypersecretion with pancreatic islet cell tumor) 251.5
    • Zollinger-Ellison (gastric hypersecretion with pancreatic islet cell tumor) 251.5
  • Zollinger-Ellison syndrome (gastric hypersecretion with pancreatic islet cell tumor) 251.5
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 251.5 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.