Specific code 2014 ICD-9-CM Diagnosis Code 157.4
Malignant neoplasm of islets of langerhans
  • Billable Code
  • Short description: Mal neo islet langerhans.
  • ICD-9-CM 157.4 will be replaced by an equivalent ICD-10-CM code (or codes) when the United States transitions from ICD-9-CM to ICD-10-CM on October 1, 2015.
  • ICD-9-CM 157.4 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
Disease Synonyms
  • Cancer of the islets of langerhans
  • Islets of langerhans cancer
  • Primary malignant neoplasm of islets of Langerhans
Clinical Information
  • (eye-let) cancer arising from cells in the islets of langerhans, which are found in the pancreas. Also called endocrine cancer.
  • A malignant endocrine neoplasm arising from islets of langerhans of the pancreas.
  • A malignant endocrine neoplasm arising from the islets of langerhans.
  • A primary malignant neoplasm of the pancreatic islet cells. Usually it involves the non-insulin-producing cell types, the pancreatic alpha cells and the pancreatic delta cells (somatostatin-secreting cells) in glucagonoma and somatostatinoma, respectively.
  • An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 hpf. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma.
  • Cancer arising from cells in the islets of langerhans, which are found in the pancreas.
Applies To
  • Islets of Langerhans, any part of pancreas
Use Additional
  • Use additional code to identify any functional activity
Convert to ICD-10-CM: 157.4 converts directly to:
  • 2014 ICD-10-CM C25.4 Malignant neoplasm of endocrine pancreas
ICD-9-CM Volume 2 Index entries containing back-references to 157.4:
  • Adenocarcinoma (M8140/3) - see also Neoplasm, by site, malignant
    • islet cell (M8150/3)
      • and exocrine, mixed (M8154/3)
        • specified site - see Neoplasm, by site, malignant
        • unspecified site 157.9
      • pancreas 157.4
      • specified site NEC - see Neoplasm, by site, malignant
      • unspecified site 157.4
  • Carcinoma (M8010/3) - see also Neoplasm, by site, malignant
    • islet cell (M8150/3)
      • and exocrine, mixed (M8154/3)
        • specified site - see Neoplasm, by site, malignant
        • unspecified site 157.9
      • pancreas 157.4
      • specified site NEC - see Neoplasm, by site, malignant
      • unspecified site 157.4
  • Gastrinoma (M8153/1)
    • malignant (M8153/3)
      • pancreas 157.4
      • specified site NEC - see Neoplasm, by site, malignant
      • unspecified site 157.4
  • Glucagonoma (M8152/0)
    • malignant (M8152/3)
      • pancreas 157.4
      • specified site NEC - see Neoplasm, by site, malignant
      • unspecified site 157.4
  • Insulinoma (M8151/0)
    • malignant (M8151/3)
      • pancreas 157.4
      • specified site - see Neoplasm, by site, malignant
      • unspecified site 157.4
  • Tumor (M8000/1) - see also Neoplasm, by site, unspecified nature
    • alpha cell (M8152/0)
      • malignant (M8152/3)
        • pancreas 157.4
        • specified site NEC - see Neoplasm, by site, malignant
        • unspecified site 157.4
      • pancreas 211.7
      • specified site NEC - see Neoplasm, by site, benign
      • unspecified site 211.7
    • beta cell (M8151/0)
      • malignant (M8151/3)
        • pancreas 157.4
        • specified site - see Neoplasm, by site, malignant
        • unspecified site 157.4
      • pancreas 211.7
      • specified site NEC - see Neoplasm, by site, benign
      • unspecified site 211.7
    • G cell (M8153/1)
      • malignant (M8153/3)
        • pancreas 157.4
        • specified site NEC - see Neoplasm, by site, malignant
        • unspecified site 157.4
      • specified site - see Neoplasm, by site, uncertain behavior
      • unspecified site 235.5
    • islet cell (M8150/0)
      • malignant (M8150/3)
        • pancreas 157.4
        • specified site - see Neoplasm, by site, malignant
        • unspecified site 157.4
      • pancreas 211.7
      • specified site NEC - see Neoplasm, by site, benign
      • unspecified site 211.7
ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. ICD-9-CM 157.4 is one of thousands of ICD-9-CM codes used in healthcare. Although ICD-9-CM and CPT codes are largely numeric, they differ in that CPT codes describe medical procedures and services. Can't find a code? Start at the root of ICD-9-CM, check the 2014 ICD-9-CM Index or use the search engine at the top of this page to lookup any code.