2012 ICD-9-CM Diagnosis Code 758.0
Down's syndrome
- A chromosomal abnormality consisting of the presence of a third copy of chromosome 21 in somatic cells.
- A disorder caused by the presence of an extra chromosome 21 and characterized by mental retardation and distinguishing physical features.
- chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21; clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, simian crease, and moderate to severe mental retardation.
- The most frequently occurring mental retardation/multiple anomaly syndrome usually involving more than 100 individual defects. Typical facies with upslanting palpebral fissures is the characteristic feature of this syndrome (hence the offensive designations "mongoloid idiocy" and "mongolism"). A wide range other defects, such as congenital heart diseases, respiratory disorders, and leukemia, may be associated. Down syndrome patients who survive into late adulthood may develop Alzheimer syndrome.
- A chromosomal dysgenesis syndrome resulting from a triplication or translocation of chromosome 21. Down syndrome occurs in approximately 1:700 live births. Abnormalities are variable from individual to individual and may include mental retardation, retarded growth, flat hypoplastic face with short nose, prominent epicanthic skin folds, small low-set ears with prominent antihelix, fissured and thickened tongue, laxness of joint ligaments, pelvic dysplasia, broad hands and feet, stubby fingers, transverse palmar crease, lenticular opacities and heart disease. Patients with Down syndrome have an estimated 10 to 30-fold increased risk for leukemia; most have symptoms of Alzheimer's disease by age 40. Also known as trisomy 21 syndrome. --2004
- ICD-9-CM 758.0 is a billable medical code that can be used to specify a diagnosis on a reimbursement claim.
- You are viewing the 2012 version of ICD-9-CM 758.0.
- More recent version(s) of ICD-9-CM 758.0: 2013.
Applies To
Convert 758.0 to ICD-10-CM 
ICD-9-CM Volume 2 Index entries containing back-references to 758.0:
autosomes NEC 
13 
