
Other endocrine disorders

Delay in sexual development and puberty not elsewhere classified
- Unusually late sexual maturity.

Precocious sexual development and puberty not elsewhere classified
- unusually early sexual maturity.

Carcinoid syndrome

Ectopic hormone secretion not elsewhere classified

Dwarfism not elsewhere classified
- condition of being undersized as a result of premature arrest of skeletal growth.

Androgen insensitivity syndrome

Androgen insensitivity, unspecified

Androgen insensitivity syndrome
- aspects of female morphology in a XY genotype caused by defects in cellular receptors for testosterone and dihydrotestosterone, transmitted as an x-linked trait.
- Sexual ambiguity in males due to a sexual differentiation disorder caused by testicular failure to respond to androgens. The affected males have abdominal and inguinal testes, female external genitalia and breasts, blind vaginas, and absent uteri. Some patients have absent pubic and axillary hair, hence the synonym "hairless pseudofemale." Mental retardation occurs in some cases.

Partial androgen insensitivity

Other specified endocrine disorders
- autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcifications, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.
- Werner Syndrome (WS) is an inherited disease characterized by an early onset of atherosclerosis, osteoporosis, diabetes mellitus, and cancers of non-epithelial cell origin. Cultured cells from WS patients also present a shortened replicative lifespan and increased genetic instability. The genomic instability of WS cells is manifested at the cytogenetic level in the form of chromosome breaks and translocations, and at the molecular level predominately by multiple, large DNA deletions. (J. Biol. Chem., 273(51):34139-34144, 1998)

Unspecified endocrine disorder
- impairment of health or a condition of abnormal functioning of the system of glands that release their secretions (hormones) directly into the circulatory system.
- Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs. (NCI)
- Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs.