
Symptoms involving skin and other integumentary tissue

Disturbance of skin sensation
- Consisting of abnormally decreased sensitivity, particularly to touch.
- Impairment of tactile sensitivity manifesting as partial loss of sensitivity to sensory stimuli.
- Abnormal touch sensations, such as burning or prickling, that occur without an outside stimulus.
- A sensation as of repetitive pin pricks, caused by cold or by striking a nerve, or as a result of various diseases of the central or peripheral nervous system.

Rash and other nonspecific skin eruption
- Any change in the skin which affects its appearance or texture. A rash may be localised to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful.

Localized superficial swelling mass or lump

Edema
- swelling from excessive accumulation of serous fluid in tissue.
- (eh-DEE-ma) Swelling caused by excess fluid in body tissues.
- Pathological transudate within one or more tissues.
- Accumulation of an excessive amount of watery fluid in cells or intercellular tissues.

Jaundice unspecified not of newborn
- clinical manifestation of hyperbilirubinemia, consisting of deposition of bile pigments in the skin, resulting in a yellowish staining of the skin and mucous membranes.
- (JAWN-dis) A condition in which the skin and the whites of the eyes become yellow, urine darkens, and the color of stool becomes lighter than normal. Jaundice occurs when the liver is not working properly or when a bile duct is blocked.

Cyanosis
- blueness of the skin caused by excessive amounts of deoxyhemoglobin in the skin vessels.
- Blue-colored skin caused by too little oxygen in the blood.

Pallor and flushing

Pallor
- An unusual or extreme paleness, state of decreased skin coloration.

Flushing
- A sudden reddening of the face.

Spontaneous ecchymoses
- (peh-TEH-kee-a) Pinpoint, unraised, round red spots under the skin caused by bleeding.

Changes in skin texture

Other symptoms involving skin and integumentary tissues