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2008 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of The Genitourinary System 580-629 > Nephritis, Nephrotic Syndrome, And Nephrosis 580-589 > 2008 ICD-9-CM Diagnosis 581 Nephrotic syndrome Clinical association of heavy PROTEINURIA, HYPOALBUMINEMIA, and generalized EDEMA. 581 is a non-specific code that cannot be used to specify a diagnosis