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2008 ICD-9-CM Volume 1 Diagnosis Codes Home > Endocrine, Nutritional And Metabolic Diseases, And Immunity Disorders 240-279 > Diseases Of Other Endocrine Glands 250-259 > Diseases Of Thymus Gland 254.* > 2008 ICD-9-CM Diagnosis 254.0 Persistent hyperplasia of thymus  On October 1, 2008 the 2009 ICD-9-CM codes came into effect. Therefore, this code may be out of date. The 2009 version of ICD-9-CM 254.0 can be accessed here. Enlargement of the thymus. A condition described in the late 1940's and 1950's as pathological thymic hypertrophy was status thymolymphaticus and was treated with radiotherapy. Unnecessary removal of the thymus was also practiced. It later became apparent that the thymus undergoes normal physiological hypertrophy, reaching a maximum at puberty and involuting thereafter. The concept of status thymolymphaticus has been abandoned. Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (From Segen, Dictionary of Modern Medicine, 1992; Cecil Textbook of Medicine, 19th ed, p1486) 254.0 is a specific code that can be used to specify a diagnosis 254.0 contains 4 index entries View the ICD-9-CM Volume 1 254.* hierarchy 254.0 also known as: Hypertrophy of thymus Index entries containing 254.0: Enlargement, enlarged - see also Hypertrophy thymus (congenital) (gland) 254.0 Hyperplasia, hyperplastic thymus (gland) (persistent) 254.0 Hypertrophy, hypertrophic thymic, thymus (congenital) (gland) 254.0 Persistence, persistent (congenital) 759.89 thymus (gland) 254.8 hyperplasia 254.0