
Diabetes mellitus
- heterogeneous group of disorders that share glucose intolerance in common.
- (dye-a-BEE-teez) A disease in which the body does not properly control the amount of sugar in the blood. As a result, the level of sugar in the blood is too high. This disease occurs when the body does not produce enough insulin or does not use it properly.
- Type 2 diabetes, characterized by target-tissue resistance to insulin, is epidemic in industrialized societies and is strongly associated with obesity; however, the mechanism by which increased adiposity causes insulin resistance is unclear. Adipocytes secrete a unique signalling molecule, which was named resistin (for resistance to insulin). Circulating resistin levels are decreased by the anti-diabetic drug rosiglitazone, and increased in diet-induced and genetic forms of obesity. Administration of anti-resistin antibody improves blood sugar and insulin action in mice with diet-induced obesity. Moreover, treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucose uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment. Resistin is thus a hormone that potentially links obesity to diabetes.

Diabetes mellitus without mention of complication
- heterogeneous group of disorders that share glucose intolerance in common.
- (dye-a-BEE-teez) A disease in which the body does not properly control the amount of sugar in the blood. As a result, the level of sugar in the blood is too high. This disease occurs when the body does not produce enough insulin or does not use it properly.
- Type 2 diabetes, characterized by target-tissue resistance to insulin, is epidemic in industrialized societies and is strongly associated with obesity; however, the mechanism by which increased adiposity causes insulin resistance is unclear. Adipocytes secrete a unique signalling molecule, which was named resistin (for resistance to insulin). Circulating resistin levels are decreased by the anti-diabetic drug rosiglitazone, and increased in diet-induced and genetic forms of obesity. Administration of anti-resistin antibody improves blood sugar and insulin action in mice with diet-induced obesity. Moreover, treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucose uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment. Resistin is thus a hormone that potentially links obesity to diabetes.

Diabetes mellitus without complication type ii or unspecified type not stated as uncontrolled

Diabetes mellitus without complication type i not stated as uncontrolled

Diabetes mellitus without complication type ii or unspecified type uncontrolled

Diabetes mellitus without complication type i uncontrolled

Diabetes with ketoacidosis
- complication of diabetes resulting from severe insulin deficiency coupled with an absolute or relative increase in glucagon concentration; metabolic acidosis is caused by the breakdown of adipose stores and resulting increased levels of free fatty acids; glucagon accelerates the oxidation of the free fatty acids producing excess ketone bodies (ketosis).
- A type of metabolic acidosis produced by accumulation of ketone bodies resulting from uncontrolled diabetes mellitus.
- The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Diabetes mellitus with ketoacidosis type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with ketoacidosis type i not stated as uncontrolled

Diabetes mellitus with ketoacidosis type ii or unspecified type uncontrolled

Diabetes mellitus with ketoacidosis type i uncontrolled

Diabetes with hyperosmolarity

Diabetes mellitus with hyperosmolarity type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with hyperosmolarity type i not stated as uncontrolled

Diabetes mellitus with hyperosmolarity type ii or unspecified type uncontrolled

Diabetes mellitus with hyperosmolarity type i uncontrolled

Diabetes with other coma

Diabetes mellitus with other coma type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with other coma type i not stated as uncontrolled

Diabetes mellitus with other coma type ii or unspecified type uncontrolled

Diabetes mellitus with other coma type i uncontrolled

Diabetes with renal manifestations
- kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney; features include increased urine protein and declining kidney function.

Diabetes mellitus with renal manifestations type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with renal manifestations type i not stated as uncontrolled

Diabetes mellitus with renal manifestations type ii or unspecified type uncontrolled

Diabetes mellitus with renal manifestations type i uncontrolled

Diabetes with ophthalmic manifestations

Diabetes mellitus with ophthalmic manifestations type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with ophthalmic manifestations type i not stated as uncontrolled

Diabetes mellitus with ophthalmic manifestations type ii or unspecified type uncontrolled

Diabetes mellitus with ophthalmic manifestations type i uncontrolled

Diabetes with neurological manifestations
- common complication of diabetes mellitus in which nerves are damaged as a result of hyperglycemia (high blood sugar levels).

Diabetes mellitus with neurological manifestations type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with neurological manifestations type i not stated as uncontrolled

Diabetes mellitus with neurological manifestations type ii or unspecified type uncontrolled

Diabetes mellitus with neurological manifestations type i uncontrolled

Diabetes with peripheral circulatory disorders

Diabetes mellitus with peripheral circulatory disorders type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with peripheral circulatory disorders type i not stated as uncontrolled

Diabetes mellitus with peripheral circulatory disorders type ii or unspecified type uncontrolled

Diabetes mellitus with peripheral circulatory disorders type i uncontrolled

Diabetes with other specified manifestations

Diabetes mellitus with other specified manifestations type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with other specified manifestations type i not stated as uncontrolled

Diabetes mellitus with other specified manifestations type ii or unspecified type uncontrolled

Diabetes mellitus with other specified manifestations type i uncontrolled

Diabetes with unspecified complication

Diabetes mellitus with unspecified complication type ii or unspecified type not stated as uncontrolled

Diabetes mellitus with unspecified complication type i not stated as uncontrolled

Diabetes mellitus with unspecified complication type ii or unspecified type uncontrolled

Diabetes mellitus with unspecified complication type i uncontrolled