Other malignant neoplasms of lymphoid and histiocytic tissue 202- >
A neoplasm of follicle centre b cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-hodgkin lymphomas in the United States And 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as grade 1, grade 2, and grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the bcl-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from who, 2001).
A neoplasm of lymphoid cells which has at least a partial follicular pattern.
A type of b-cell non-hodgkin lymphoma (cancer of the immune system) that is usually indolent (slow-growing). The tumor cells grow as groups to form nodules. There are several subtypes of follicular lymphoma.
Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal center of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center b-lymphocytes.
202Other malignant neoplasms of lymphoid and histiocytic tissue