- Splenoptosis 289.59
- Splinter - see Injury, superficial, by site
- Split, splitting
- Spoiled child reaction (see also Disturbance, conduct) 312.1
- Spondylarthritis (see also Spondylosis) 721.90
- Spondylarthrosis (see also Spondylosis) 721.90
- Spondylitis 720.9
- Spondyloarthrosis (see also Spondylosis) 721.90
- Spondylolisthesis (congenital) (lumbosacral) 756.12
- Spondylolysis (congenital) 756.11
- Spondylopathy
- Spondylose rhizomelique 720.0
- Spondylosis 721.90
- Sponge
- Spongioblastoma (M9422/3)
- Spongiocytoma (M9400/3)
- Spongioneuroblastoma (M9504/3) - see Neoplasm, by site, malignant
- Spontaneous - see also condition
- Spoon nail 703.8
- Sporadic - see condition
- Sporotrichosis (bones) (cutaneous) (disseminated) (epidermal) (lymphatic) (lymphocutaneous) (mucous membranes) (pulmonary) (skeletal) (visceral) 117.1
- Sporotrichum schenckii infection 117.1
