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2007 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of The Nervous System And Sense Organs 320-389 > Hereditary And Degenerative Diseases Of The Central Nervous System 330-338 > Anterior Horn Cell Disease 335.* > 2007 ICD-9-CM Diagnosis 335.20 Amyotrophic lateral sclerosis This code may be outdated. View the most recent version of ICD-9-CM 335.20 A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) 335.20 is a specific code that can be used to specify a diagnosis 335.20 contains 12 index entries View the ICD-9-CM Volume 1 335.* hierarchy 335.20 also known as: Motor neuron disease (bulbar) (mixed type) Index entries containing 335.20: Amyotrophia, amyotrophy, amyotrophic 728.2 lateral sclerosis (syndrome) 335.20 sclerosis (lateral) 335.20 Atrophy, atrophic palsy, diffuse 335.20 Disease, diseased - see also Syndrome Lou Gehrig's 335.20 motor neuron (bulbar) (mixed type) 335.20 Lou Gehrig's disease 335.20 Palsy (see also Paralysis) 344.9 atrophic diffuse 335.20 Paralysis, paralytic (complete) (incomplete) 344.9 amyotrophic 335.20 progressive 335.21 multiple 335.20 Sclerosis, sclerotic amyotrophic (lateral) 335.20 lateral 335.24 amyotrophic 335.20 Syndrome - see also Disease amyotrophic lateral sclerosis 335.20