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2007 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of The Nervous System And Sense Organs 320-389 > Hereditary And Degenerative Diseases Of The Central Nervous System 330-338 > Other Cerebral Degenerations 331.* > 2007 ICD-9-CM Diagnosis 331.81 Reye's syndrome This code may be outdated. View the most recent version of ICD-9-CM 331.81 A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism. 331.81 is a specific code that can be used to specify a diagnosis 331.81 contains 2 index entries View the ICD-9-CM Volume 1 331.* hierarchy Index entries containing 331.81: Reye's syndrome 331.81 Syndrome - see also Disease Reye's 331.81