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2007 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of Blood And Blood-Forming Organs 280-289 > Other Diseases Of Blood And Blood-Forming Organs 289.* > 2007 ICD-9-CM Diagnosis 289.4 Hypersplenism This code may be outdated. View the most recent version of ICD-9-CM 289.4 Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow, and the potential for reversal by splenectomy. 289.4 is a specific code that can be used to specify a diagnosis 289.4 contains 10 index entries View the ICD-9-CM Volume 1 289.* hierarchy 289.4 also known as: "Big spleen" syndrome Dyssplenism Hypersplenia 289.4 excludes: primary splenic neutropenia (289.53) Index entries containing 289.4: Aleukia splenica 289.4 Big spleen syndrome 289.4 Dyssplenism 289.4 Hypersplenia 289.4 Hypersplenism 289.4 Hypoleukia splenica 289.4 Increase, increased splenic activity 289.4 Panhematopenia 284.8 splenic, primary 289.4 Syndrome - see also Disease big spleen 289.4 hypersplenic 289.4