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2007 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of Blood And Blood-Forming Organs 280-289 > Other Deficiency Anemias 281.* > 2007 ICD-9-CM Diagnosis 281.0 Pernicious anemia This code may be outdated. View the most recent version of ICD-9-CM 281.0 (per-NISH-us a-NEE-mee-a) A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12. A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed) 281.0 is a specific code that can be used to specify a diagnosis 281.0 contains 20 index entries View the ICD-9-CM Volume 1 281.* hierarchy 281.0 also known as: Anemia: Addison's Biermer's congenital pernicious Congenital intrinsic factor [Castle's] deficiency 281.0 excludes: combined system disease without mention of anemia (266.2) subacute degeneration of spinal cord without mention of anemia (266.2) Index entries containing 281.0: Addison's anemia (pernicious) 281.0 Addison-Biermer anemia (pernicious) 281.0 Anemia 285.9 Addison's (pernicious) 281.0 Addison-Biermer (pernicious) 281.0 Biermer's (pernicious) 281.0 congenital (following fetal blood loss) 776.5 pernicious 281.0 cytogenic 281.0 deficiency 281.9 vitamin B12 NEC 281.1 pernicious 281.0 malignant (progressive) 281.0 pernicious (combined system disease) (congenital) (dorsolateral spinal degeneration) (juvenile) (myelopathy) (neuropathy) (posterior sclerosis) (primary) (progressive) (spleen) 281.0 of or complicating pregnancy 648.2 progressive 285.9 malignant 281.0 pernicious 281.0 vitamin B12 deficiency (dietary) 281.1 pernicious 281.0 Biermer's anemia or disease (pernicious anemia) 281.0 Congenital - see also condition intrinsic factor deficiency 281.0 Deficiency, deficient intrinsic factor (Castle's) (congenital) 281.0 Disease, diseased - see also Syndrome Addison's (bronze) (primary adrenal insufficiency) 255.4 anemia (pernicious) 281.0 Biermer's (pernicious anemia) 281.0 Runeberg's (progressive pernicious anemia) 281.0 Runeberg's disease (progressive pernicious anemia) 281.0