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2007 ICD-9-CM Volume 1 Diagnosis Codes Home > Endocrine, Nutritional And Metabolic Diseases, And Immunity Disorders 240-279 > Diseases Of Other Endocrine Glands 250-259 > Disorders Of Adrenal Glands 255.* > 2007 ICD-9-CM Diagnosis 255.0 Cushing's syndrome  On October 1, 2008 the 2009 ICD-9-CM codes came into effect. Therefore, this code may be out of date. The 2009 version of ICD-9-CM 255.0 can be accessed here. A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent. A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME. Abnormal secretion of adrenocorticotrophic hormone in conjunction with neoplastic growth occurring anywhere in the body. The most common associations are tumors of the bronchus (oat cell or carcinoid), thymic tumors (epithelial or carcinoid), pancreatic endocrine tumor. (DeVita et al. Cancer, p 1364. 4th edition. Lippincott) Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM. Symptom complex due to ACTH production by non-pituitary neoplasms. 255.0 is a specific code that can be used to specify a diagnosis 255.0 contains 18 index entries View the ICD-9-CM Volume 1 255.* hierarchy 255.0 also known as: Adrenal hyperplasia due to excess ACTH Cushing's syndrome: NOS iatrogenic idiopathic pituitary-dependent Ectopic ACTH syndrome Iatrogenic syndrome of excess cortisol Overproduction of cortisol Use additional E code to identify cause, if drug-induced 255.0 excludes: congenital adrenal hyperplasia (255.2) Index entries containing 255.0: Basophilism (corticoadrenal) (Cushing's) (pituitary) (thymic) 255.0 Cushing's basophilism, disease, or syndrome (iatrogenic) (idiopathic) (pituitary basophilism) (pituitary dependent) 255.0 Cushingoid due to steroid therapy correct substance properly administered 255.0 Disease, diseased - see also Syndrome Cushing's (pituitary basophilism) 255.0 Ectopic, ectopia (congenital) 759.89 ACTH syndrome 255.0 secretion ACTH 255.0 adrenocorticotropin 255.0 Hyperplasia, hyperplastic adrenal (capsule) (cortex) (gland) 255.8 due to excess ACTH (ectopic) (pituitary) 255.0 Hypersecretion cortisol 255.0 Iatrogenic syndrome of excess cortisol 255.0 Inappropriate secretion ACTH 255.0 Itsenko-Cushing syndrome (pituitary basophilism) 255.0 Overproduction - see also Hypersecretion cortisol 255.0 Steroid effects (adverse) (iatrogenic) cushingoid correct substance properly administered 255.0 Syndrome - see also Disease Cushing's (iatrogenic) (idiopathic) (pituitary basophilism) (pituitary-dependent) 255.0 overdose or wrong substance given or taken 962.0 ectopic ACTH secretion 255.0 excess cortisol, iatrogenic 255.0 Itsenko-Cushing (pituitary basophilism) 255.0