
Other malignant neoplasms of lymphoid and histiocytic tissue

Nodular lymphoma
- A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

Nodular lymphoma unspecified site

Nodular lymphoma involving lymph nodes of head face and neck

Nodular lymphoma involving intrathoracic lymph nodes

Nodular lymphoma involving intra-abdominal lymph nodes

Nodular lymphoma involving lymph nodes of axilla and upper limb

Nodular lymphoma involving lymph nodes of inguinal region and lower limb

Nodular lymphoma involving intrapelvic lymph nodes

Nodular lymphoma involving spleen

Nodular lymphoma involving lymph nodes of multiple sites

Mycosis fungoides
- (mye-KO-sis fun-GOY-deez) A type of non-Hodgkin's lymphoma that first appears on the skin and can spread to the lymph nodes or other organs such as the spleen, liver, or lungs.
- chronic malignant T-cell lymphoma of the skin; in the late stages the lymph nodes and viscera are affected.
- A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques. It is characterized by epidermal and dermal infiltration of small to medium-sized T-cells with cerebriform nuclei. Patients with limited disease generally have an excellent prognosis. In the more advanced stages, the prognosis is poor. (WHO, 2001)

Mycosis fungoides unspecified site

Mycosis fungoides involving lymph nodes of head face and neck

Mycosis fungoides involving intrathoracic lymph nodes

Mycosis fungoides involving intra-abdominal lymph nodes

Mycosis fungoides involving lymph nodes of axilla and upper limb

Mycosis fungoides involving lymph nodes of inguinal region and lower limb

Mycosis fungoides involving intrapelvic lymph nodes

Mycosis fungoides involving spleen

Mycosis fungoides involving lymph nodes of multiple sites

Sezary's disease
- A form of cutaneous T-cell lymphoma, a cancerous disease that affects the skin.
- A generalized peripheral (mature) T-cell neoplasm characterized by the presence of erythroderma, lymphadenopathy, and neoplastic, cerebriform T-lymphocytes in the blood. Sezary syndrome is an aggressive disease. (WHO, 2001)

Sezary's disease unspecified site

Sezary's disease involving lymph nodes of head face and neck

Sezary's disease involving intrathoracic lymph nodes

Sezary's disease involving intra-abdominal lymph nodes

Sezary's disease involving lymph nodes of axilla and upper limb

Sezary's disease involving lymph nodes of inguinal region and lower limb

Sezary's disease involving intrapelvic lymph nodes

Sezary's disease involving spleen

Sezary's disease involving lymph nodes of multiple sites

Malignant histiocytosis
- An antiquated term referring to cases of systemic non-Hodgkin lymphomas which are composed of large, atypical neoplastic lymphoid cells and cases of hemophagocytic syndromes. In the past, cases of anaplastic large cells lymphoma were called malignant histiocytosis.

Malignant histiocytosis unspecified site

Malignant histiocytosis involving lymph nodes of head face and neck

Malignant histiocytosis involving intrathoracic lymph nodes

Malignant histiocytosis involving intra-abdominal lymph nodes

Malignant histiocytosis involving lymph nodes of axilla and upper limb

Malignant histiocytosis involving lymph nodes of inguinal region and lower limb

Malignant histiocytosis involving intrapelvic lymph nodes

Malignant histiocytosis involving spleen

Malignant histiocytosis involving lymph nodes of multiple sites

Leukemic reticuloendotheliosis
- neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.
- A type of chronic leukemia in which the abnormal white blood cells appear to be covered with tiny hairs when viewed under a microscope.
- A rare neoplasm of small B-lymphocytes with "hairy" projections in bone marrow, spleen, and peripheral blood. Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia. (WHO, 2001)

Leukemic reticuloendotheliosis unspecified site

Leukemic reticuloendotheliosis involving lymph nodes of head face and neck

Leukemic reticuloendotheliosis involving intrathoracic lymph nodes

Leukemic reticuloendotheliosis involving intra-abdominal lymph nodes

Leukemic reticuloendotheliosis involving lymph nodes of axilla and upper arm

Leukemic reticuloendotheliosis involving lymph nodes of inguinal region and lower limb

Leukemic reticuloendotheliosis involving intrapelvic lymph nodes

Leukemic reticuloendotheliosis involving spleen

Leukemic reticuloendotheliosis involving lymph nodes of multiple sites

Letterer-siwe disease
- A multifocal, multisystem form of Langerhans-cell histiocytosis. There is involvement of multiple organ systems including the bones, skin, liver, spleen, and lymph nodes. Patients are usually infants presenting with fever, hepatosplenomegaly, lymphadenopathy, bone and skin lesions, and pancytopenia.

Letterer-siwe disease unspecified site

Letterer-siwe disease involving lymph nodes of head face and neck

Letterer-siwe disease involving intrathoracic lymph nodes

Letterer-siwe disease involving intra-abdominal lymph nodes

Letterer-siwe disease involving lymph nodes of axilla and upper limb

Letterer-siwe disease involving lymph nodes of inguinal region and lower limb

Letterer-siwe disease involving intrapelvic lymph nodes

Letterer-siwe disease involving spleen

Letterer-siwe disease involving lymph nodes of multiple sites

Malignant mast cell tumors
- A rare entity characterized by localized but destructive growth of a tumor consisting of highly atypical, immature mast cells.(WHO, 2001)
- A variant of mastocytosis characterized by multifocal, dense infiltrates of mast cells (15 or more mast cells in aggregates) detected in the bone marrow and/or other extracutaneous sites. (WHO, 2001) -- 2003
- Malignant neoplasm originating from mast cells.

Malignant mast cell tumors unspecified site

Malignant mast cell tumors involving lymph nodes of head face and neck

Malignant mast cell tumors involving intrathoracic lymph nodes

Malignant mast cell tumors involving intra-abdominal lymph nodes

Malignant mast cell tumors involving lymph nodes of axilla and upper limb

Malignant mast cell tumors involving lymph nodes of inguinal region and lower limb

Malignant mast cell tumors involving intrapelvic lymph nodes

Malignant mast cell tumors involving spleen

Malignant mast cell tumors involving lymph nodes of multiple sites

Other malignant lymphomas
- malignant (clonal) proliferation of B- or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites; general term for various neoplastic diseases of the lymphoid tissue.
- (lim-FO-ma) Cancer that arises in cells of the lymphatic system.
- A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.
- malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organized pattern; patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern.
- An obsolete term for a malignant tumor of lymphatic tissue.

Other malignant lymphomas unspecified site

Other malignant lymphomas involving lymph nodes of head face and neck

Other malignant lymphomas involving intrathoracic lymph nodes

Other malignant lymphomas involving intra-abdominal lymph nodes

Other malignant lymphomas involving lymph nodes of axilla and upper limb

Other malignant lymphomas involving lymph nodes of inguinal region and lower limb

Other malignant lymphomas involving intrapelvic lymph nodes

Other malignant lymphomas involving spleen

Other malignant lymphomas involving lymph nodes of multiple sites

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue
- Malignant neoplasms that either originate from the bone marrow (e.g. myeloid leukemias) or involve the bone marrow as secondary-metastatic tumors (e.g. metastatic carcinomas to the bone marrow). --2003
- A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features. It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001)

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue unspecified site

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving lymph nodes of head face and neck

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving intrathoracic lymph nodes

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving intra-abdominal lymph nodes

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving lymph nodes of axilla and upper limb

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving lymph nodes of inguinal region and lower limb

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving intrapelvic lymph nodes

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving spleen

Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue involving lymph nodes of multiple sites