- Spermatic cord - see condition
- Spermatocele 608.1
- Spermatocystitis 608.4
- Spermatocytoma (M9063/3)
- Spermatorrhea 608.89
- Sphacelus (see also Gangrene) 785.4
- Sphenoidal - see condition
- Sphenoiditis (chronic) (see also Sinusitis, sphenoidal) 473.3
- Sphenopalatine ganglion neuralgia 337.0
- Sphericity, increased, lens 743.36
- Spherocytosis (congenital) (familial) (hereditary) 282.0
- Spherophakia 743.36
- Sphincter - see condition
- Sphincteritis, sphincter of Oddi (see also Cholecystitis) 576.8
- Sphingolipidosis 272.7
- Sphingolipodystrophy 272.7
- Sphingomyelinosis 272.7
- Spicule tooth 520.2
- Spider
- Spiegler-Fendt sarcoid 686.8
- Spielmeyer-Stock disease 330.1
- Spielmeyer-Vogt disease 330.1
