2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of The Nervous System And Sense Organs 320-389 > Disorders Of The Eye And Adnexa 360-379 > Other Disorders Of Eye 379.* > 2006 ICD-9-CM Diagnosis 379.46 Tonic pupillary reaction View the most recent version of ICD-9-CM 379.46 A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. A pupillary abnormality characterized by a poor pupillary light reaction, reduced accommodation, iris sector palsies, an enhanced pupillary response to near effort that results in a prolonged, "tonic" constriction, and slow pupillary redilation. This condition is associated with injury to the postganglionic parasympathetic innervation to the pupil. 379.46 is a specific code that can be used to specify a diagnosis 379.46 contains 11 index entries View the ICD-9-CM Volume 1 379.* hierarchy Alternate Terminology Adie's pupil or syndrome  Index entries containing 379.46: Adie (-Holmes) syndrome (tonic pupillary reaction) 379.46 Myotonic pupil 379.46 Pupillotonia 379.46 pseudotabetic 379.46 Reaction pupillary (myotonic) (tonic) 379.46 Saenger's syndrome 379.46 Syndrome - see also Disease Adie (-Holmes) (pupil) 379.46 Holmes-Adie 379.46 Markus-Adie 379.46 Saenger's 379.46 Tonic pupil 379.46