2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of The Nervous System And Sense Organs 320-389 > Hereditary And Degenerative Diseases Of The Central Nervous System 330-338 > ICD-9-CM Diagnosis 335 Anterior horn cell disease 335 is a non-specific code that cannot be used to specify a diagnosis ICD-9-CM Diagnosis 335.0 Werdnig-hoffmann disease 335.0 is a specific code that can be used to specify a diagnosis 335.0 contains 9 index entries ICD-9-CM Diagnosis 335.1 Spinal muscular atrophy A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. 335.1 is a non-specific code that cannot be used to specify a diagnosis ICD-9-CM Diagnosis 335.10 Spinal muscular atrophy unspecified A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. 335.10 is a specific code that can be used to specify a diagnosis 335.10 contains 7 index entries ICD-9-CM Diagnosis 335.11 Kugelberg-welander disease 335.11 is a specific code that can be used to specify a diagnosis 335.11 contains 11 index entries ICD-9-CM Diagnosis 335.19 Other spinal muscular atrophy 335.19 is a specific code that can be used to specify a diagnosis 335.19 contains 4 index entries ICD-9-CM Diagnosis 335.2 Motor neuron disease Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. 335.2 is a non-specific code that cannot be used to specify a diagnosis ICD-9-CM Diagnosis 335.20 Amyotrophic lateral sclerosis A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. 335.20 is a specific code that can be used to specify a diagnosis 335.20 contains 12 index entries ICD-9-CM Diagnosis 335.21 Progressive muscular atrophy 335.21 is a specific code that can be used to specify a diagnosis 335.21 contains 23 index entries ICD-9-CM Diagnosis 335.22 Progressive bulbar palsy A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115 335.22 is a specific code that can be used to specify a diagnosis 335.22 contains 12 index entries ICD-9-CM Diagnosis 335.23 Pseudobulbar palsy A syndrome characterized by DYSARTHRIA, dysphagia, dysphonia, impairment of voluntary movements of tongue and facial muscles, and emotional lability. This condition is caused by diseases that affect the motor fibers that travel from the cerebral cortex to the lower BRAIN STEM (i.e., corticobulbar tracts); including MULTIPLE SCLEROSIS; MOTOR NEURON DISEASE; and CEREBROVASCULAR DISORDERS. 335.23 is a specific code that can be used to specify a diagnosis 335.23 contains 4 index entries ICD-9-CM Diagnosis 335.24 Primary lateral sclerosis 335.24 is a specific code that can be used to specify a diagnosis 335.24 contains 7 index entries ICD-9-CM Diagnosis 335.29 Other motor neuron diseases 335.29 is a specific code that can be used to specify a diagnosis 335.29 contains 2 index entries ICD-9-CM Diagnosis 335.8 Other anterior horn cell diseases 335.8 is a specific code that can be used to specify a diagnosis 335.8 contains 1 index entry ICD-9-CM Diagnosis 335.9 Anterior horn cell disease unspecified 335.9 is a specific code that can be used to specify a diagnosis 335.9 contains 3 index entries