2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Mental Disorders 290-319 > Neurotic Disorders, Personality Disorders, And Other Nonpsychotic Mental Disorders 300-316 > 2006 ICD-9-CM Diagnosis 304 Drug dependence View the most recent version of ICD-9-CM 304 Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug. 304 is a non-specific code that cannot be used to specify a diagnosis 304 Excludes nondependent abuse of drugs (305.1-305.9)