2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Diseases Of Blood And Blood-Forming Organs 280-289 > ICD-9-CM Diagnosis 288 Diseases of white blood cells Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells. 288 is a non-specific code that cannot be used to specify a diagnosis ICD-9-CM Diagnosis 288.0 Agranulocytosis A decrease in the number of GRANULOCYTES (BASOPHILS, EOSINOPHILS, and NEUTROPHILS). A deficiency in the number of granulocytes, a type of white blood cell. A decrease in the number of neutrophilic leukocytes in the blood. An abnormal decrease in the number of neutrophils, a type of white blood cell. A decrease in the number of mature granulocytes (neutrophils, eosinophils, and basophils) in the peripheral blood. -- 2004 288.0 is a specific code that can be used to specify a diagnosis 288.0 contains 47 index entries ICD-9-CM Diagnosis 288.1 Functional disorders of polymorphonuclear neutrophils A disorder of neutrophils characterized by the presence of abnormal or absent chemotactic responses and hyperimmunoglobulinemia E. It is transmitted as an autosomal recessive trait and most cases reported have been in girls. A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. 288.1 is a specific code that can be used to specify a diagnosis 288.1 contains 10 index entries ICD-9-CM Diagnosis 288.2 Genetic anomalies of leukocytes A rare autosomal recessive immunodeficiency disorder characterized by abnormal intracellular protein transport. Chediak-Higashi syndrome (CHS) is characterized by immune deficiency; partial oculocutaneous albinism; a bleeding disorder due to deficient platelet dense bodies; neutropenia; neutrophils with impaired chemotaxis and bactericidal activity; recurrent infection; and abnormal natural killer (NK) cell function. CHS may be associated with hepatosplenomegaly, lymphadenopathy, anemia, thrombocytopenia, roentgenologic changes in bones, lungs and heart, and skin and psychomotor abnormalities; it is often fatal in childhood as a result of infection or an accelerated lymphoma-like phase. CHS occurs in mink, cattle, and mice, as well as man. --2004 A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle. 288.2 is a specific code that can be used to specify a diagnosis 288.2 contains 37 index entries ICD-9-CM Diagnosis 288.3 Eosinophilia A condition in which the number of eosinophils (a type of white blood cell) in the blood is greatly increased. Eosinophilia is often a response to infection or allergens (substances that cause an allergic response). Abnormal increase in eosinophils in the blood, tissues or organs. 288.3 is a specific code that can be used to specify a diagnosis 288.3 contains 8 index entries ICD-9-CM Diagnosis 288.8 Other specified disease of white blood cells A peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone. Excess of normal lymphocytes in the blood or in any effusion. A transient increase in the number of leukocytes in a body fluid. An abnormally small number of lymphocytes in the circulating blood. Reduction in the number of lymphocytes. 288.8 is a specific code that can be used to specify a diagnosis 288.8 contains 22 index entries ICD-9-CM Diagnosis 288.9 Unspecified disease of white blood cells Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells. 288.9 is a specific code that can be used to specify a diagnosis 288.9 contains 5 index entries