2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Neoplasms 140-239 > Neoplasms Of Uncertain Behavior 235-238 > Neoplasm Of Uncertain Behavior Of Other And Unspecified Sites And Tissues 238.* > 2006 ICD-9-CM Diagnosis 238.7 Neoplasm of uncertain behavior of other lymphatic and hematopoietic tissues View the most recent version of ICD-9-CM 238.7 An increased number of thrombocytes (platelets) in the blood, without a known cause. Diseases in which too many blood cells are made in the bone marrow. A progressive disease in which the bone marrow is replaced by fibrous tissue and is unable to produce red blood cells; the cause is unknown. Chronic refractory anemia with granulocytopenia, and/or thrombocytopenia. Myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells. Abnormal bone marrow cells that may lead to myelogenous leukemia. A clonal (malignant) proliferation of myeloid (erythroid, granulocytic, or megakaryocytic) cells originating from a primitive stem cell. -- 2003 (MYE-eh-lo-dis-PLAS-tik SIN-drome) Disease in which the bone marrow does not function normally. An acute myeloid leukemia characterized by bone marrow fibrosis. The prognosis is usually poor. (WHO, 2001) -- 2003 A chronic myeloproliferative disorder characterized by bone marrow fibrosis, proliferation of atypical megakaryocytes and granulocytes in the bone marrow, anemia, splenomegaly, and extramedullary hematopoiesis. The cause is unknown. The median survival time is 3-5 years from diagnosis. (WHO, 2001) -- 2003 Conditions in which the abnormalities in the peripheral blood or bone marrow represent the early manifestations of acute leukemia, but in which the changes are not of sufficient magnitude or specificity to permit a diagnosis of acute leukemia by the usual clinical criteria. Myelodysplastic syndrome (MDS) is a clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. MDS may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) -- 2003 Conditions in which the bone marrow shows qualitative and quantitative changes suggestive of a preleukemic process, but having a chronic course that does not necessarily terminate as acute leukemia. Diseases in which cells of the lymphatic system grow excessively. These disorders are often treated like cancer. A disorder in which the bone marrow is replaced by fibrous tissue. A disorder characterized by proliferation of lymphocytes at various stages of differentiation. Lymphoproliferative disorders can be neoplastic (clonal, as in lymphomas and leukemias) or reactive (polyclonal, as in infectious mononucleosis). --2004 A chronic myeloproliferative disorder that involves primarily the megakaryocytic lineage and it is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage. The cause is unknown. Median survival times of 10-15 years are commonly reported. (WHO, 2001) -- 2003 Chronic myeloproliferative disorders (CMPDs) are clonal hematopoietic stem cell disorders, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, and megakaryocytic) lineages. The proliferation is associated with relatively normal, effective maturation, resulting in increased numbers of granulocytes, red blood cells, and/or platelets in the peripheral blood. CMPDs are primarily diseases of adults. -- 2003 A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets. Disorders in which one or more stimuli cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. Disorders characterized by proliferation of lymphoid tissue, general or unspecified. 238.7 is a specific code that can be used to specify a diagnosis 238.7 contains 23 index entries View the ICD-9-CM Volume 1 238.* hierarchy Alternate Terminology Disease: lymphoproliferative (chronic) NOS myeloproliferative (chronic) NOS Idiopathic thrombocythemia Megakaryocytic myelosclerosis Myelodysplastic syndrome Myelosclerosis with myeloid metaplasia Panmyelosis (acute) Refractory anemia 238.7 Excludes myelofibrosis (289.89) myelosclerosis NOS (289.89) myelosis: NOS (205.9) megakaryocytic (207.2)