2006 ICD-9-CM Volume 1 Diagnosis Codes Home > Infectious And Parasitic Diseases 001-139 > Viral Diseases Accompanied By Exanthem 050-057 > Smallpox 050.* > 2006 ICD-9-CM Diagnosis 050.0 Variola major View the most recent version of ICD-9-CM 050.0 An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. 050.0 is a specific code that can be used to specify a diagnosis 050.0 contains 7 index entries View the ICD-9-CM Volume 1 050.* hierarchy Alternate Terminology Hemorrhagic (pustular) smallpox Malignant smallpox Purpura variolosa  Index entries containing 050.0: Infection, infected, infective (opportunistic) 136.9 variola 050.9 major 050.0 Purpura 287.2 variolosa 050.0 Smallpox 050.9 hemorrhagic (pustular) 050.0 malignant 050.0 Variola 050.9 hemorrhagic (pustular) 050.0 major 050.0 Variolosa, purpura 050.0